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Antioxidants in leafy green vegetables offer powerful protection against cataracts, UV damage

December 26, 2004

Once again, here's how a common medical disorder (cataracts) is almost entirely preventable through nutrition. And it's not just lutein and zeaxanthin that can prevent cataracts, it's also astaxanthin, a powerful antioxidant found in microalgae.

News summary:

  • Lutein and zeaxanthin, carotenoids found in dark leafy green vegetables, were nearly 10 times more powerful than the antioxidant vitamin E in protecting human eye cells from UV-induced damage, report US researchers.
  • Their findings support previous evidence suggesting that the natural compounds could help prevent cataracts, which affect nearly 20 million people in the United States alone and require expensive, surgical treatment.
  • "Along with the many environmental, lifestyle and genetic risk factors associated with cataracts, exposure to ultraviolet radiation from sunlight and oxidative stress appear to be the most relevant in this disease," said study co-author Joshua Bomser.
  • The Ohio researchers treated human eye lens cells with varying concentrations of lutein, zeaxanthin or vitamin E. They then exposed these cells, along with a batch of untreated cells, to doses of ultraviolet-beta radiation for 10 seconds.
  • UVB radiation is thought to be the primary environmental culprit in causing skin cancer as well as initiating cataract disease.
  • "The dose of UVB radiation we used on the cells is about the same amount a person receives when they get a mild tan," Bomser said.
  • Adding lutein and zeaxanthin to the cell cultures provided double the protection from UVB damage -- the antioxidants reduced signs of damage by 50 to 60 per cent, while vitamin E only reduced the same signs of damage by 25 to 32 per cent, according to the study in this month's issue of the Journal of Nutrition.
  • "The lens is equipped with antioxidant defense mechanisms designed to guard against the harmful effects of ultraviolet radiation and oxidative stress," Bomser said.

Source:www.newstarget.com

 
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