Hope over 'obesity-busting gum'
January 16, 2007
Scientists are looking at whether
an appetite-suppressing
chewing gum could be used to tackle obesity.
The Imperial College London teams are developing a
drug based on a natural gut hormone that mimics the
body's "feeling full" response.
An injectible treatment could be available in five to eight years, but the long-term goal is to produce a form that can be absorbed in the mouth.
One in five adults are obese, but that could rise to one in three by 2010.
The hormone in question is called pancreatic polypeptide (PP), which the body produces after every meal to ensure eating does not run out of control.
There is evidence that some people have more of the hormone than others, and becoming overweight reduces the levels produced.
A vicious circle then results, causing appetite to increase, an inability to resist the temptation of food, and further increases in weight.
Early tests have shown moderate doses of the hormone, pancreatic polypeptide (PP), can reduce the amount of food eaten by healthy volunteers by 15% to 20%.
The teams have now been given funding of £2.2m from
the Wellcome Trust to take it forward.
As well as chewing gum, they believe it could be incorporated in a nasal spray.
Source from: http://news.bbc.co.uk
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